Destruction of Osseointegration

Bone resorption will occur at sites of inflammation or prolonged excessive stimulation. The main contributing factors to bone resorption are local inflammation from plaque accumulation and trauma from occlusion. Periodontal disease from plaque inflammatory response, and subsequent bone resorption can result from the following:

  • Direct action of plaque products on bone progenitor cells induce their differentiation into osteoclasts.
  • Plaque products directly on bone, destroying it through a non cellular mechanism.
  • Plaque products stimulate gingival cells, causing them to release mediators which in turn induce bone progenitor cells to differentiate in osteoclasts.
  • Plaque products cause gingival cells to release agents that can act as cofactors in bone resorption.
  • Plaque products cause gingival cells to release agents that destroy bone by direct chemical action without osteoclasts.
Resorbable Tissue Replacement (RTR) mixed with patient's blood

Resorbable Tissue Replacement (RTR) mixed with patient’s blood

4 thoughts on “Destruction of Osseointegration

  1. Abby Redder

    If you have been told you have periodontal (gum) disease, you’re not alone. Many adults in the U.S. currently have some form of the disease. Periodontal diseases range from simple gum inflammation to serious disease that results in major damage to the soft tissue and bone that support the teeth. In the worst cases, teeth are lost.

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